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alpha>Indicwiki: Created page with "{{Navbox | name = Glucocorticoid receptor modulators | title = Glucocorticoid receptor modulators | bodyclass = hlist | state = {{{state<includeonl..."
2023-02-16T05:31:37Z
<p>Created page with "{{Navbox | name = Glucocorticoid receptor modulators | title = <a href="/index.php?title=Glucocorticoid_receptor&action=edit&redlink=1" class="new" title="Glucocorticoid receptor (page does not exist)">Glucocorticoid receptor</a> <a href="/index.php?title=Receptor_modulator&action=edit&redlink=1" class="new" title="Receptor modulator (page does not exist)">modulators</a> | bodyclass = hlist | state = {{{state<includeonl..."</p>
<p><b>New page</b></p><div>{{Navbox<br />
| name = Glucocorticoid receptor modulators<br />
| title = [[Glucocorticoid receptor]] [[receptor modulator|modulator]]s<br />
| bodyclass = hlist<br />
| state = {{{state<includeonly>|collapsed</includeonly>}}}<br />
| groupstyle = text-align:center;<br />
<br />
| group1 = {{abbrlink|GR|Glucocorticoid receptor}}<br />
| list1 = {{Navbox|subgroup<br />
| groupstyle = text-align:center<br />
| groupwidth = 6em;<br />
<br />
| group1 = [[Glucocorticoid|Agonist]]s<br />
| list1 =<br />
* ''Cortisol-like and related (16-unsubstituted):'' [[Tetrahydrocorticosterone|3α,5α-Tetrahydrocorticosterone]]<br />
* [[5α-Dihydrocorticosterone]]<br />
* [[9α-Fluorocortisone|9α-Fluorocortisone (alfluorone)]]<br />
* [[11-Dehydrocorticosterone|11-Dehydrocorticosterone (11-oxocorticosterone, 17-deoxycortisone)]]<br />
** [[11-Dehydrocorticosterone acetate]]<!--11-Dehydrocorticosterone 21-acetate--><br />
* [[11-Deoxycorticosterone|11-Deoxycorticosterone (desoxycortone, deoxycortone, desoxycorticosterone)]]<br />
** [[List of corticosteroid esters#Desoxycortone esters|Desoxycortone esters]]<br />
* [[11-Deoxycortisol|11-Deoxycortisol (cortodoxone, cortexolone)]]<br />
** [[Cortifen|Cortifen (cortiphen, kortifen)]]<br />
** [[Cortodoxone acetate]]<!--Cortodoxone 21-acetate--><br />
* [[21-Deoxycortisol]]<br />
* [[Δ7-Prednisolone|Δ<sup>7</sup>-Prednisolone]]<br />
** [[Δ7-Prednisolone 21-acetate|Δ<sup>7</sup>-Prednisolone 21-acetate]]<br />
* [[Amebucort]]<br />
* [[Chloroprednisone]]<br />
** [[Chloroprednisone acetate]]<!--Chloroprednisone 21-acetate--><br />
* [[Cloprednol]]<br />
** [[Cloprednol acetate]]<!--Cloprednol 21-acetate--><br />
* [[Corticosterone]]<br />
** [[Corticosterone acetate]]<!--Corticosterone 21-acetate--><br />
** [[Corticosterone benzoate]]<!--Corticosterone 21-benzoate--><br />
* [[Cortisol]] ([[hydrocortisone]])<br />
** [[Benzodrocortisone|Benzodrocortisone (hydrocortisone benzoate)]]<!--Hydrocortisone 17α-benzoate--><br />
** [[Hydrocortamate|Hydrocortamate (hydrocortisone diethylaminoacetate)]]<!--Hydrocortisone 21-(diethylaminoacetate)--><br />
** [[List of corticosteroid esters#Hydrocortisone esters|Hydrocortisone esters]]<br />
* [[Cortisone]]<br />
** [[Cortisone acetate]]<!--Cortisone 21-acetate--><br />
* [[Deprodone]]<br />
** [[Deprodone propionate]]<!--Deprodone 17α-propionate--><br />
* [[Dichlorisone]]<br />
** [[Dichlorisone acetate]]<!--Dichlorisone 21-acetate--><br />
** [[Dichlorisone diacetate]]<!--Dichlorisone 17α,21-diacetate--><br />
* [[Difluprednate]]<br />
* [[Endrisone|Endrisone (endrysone)]]<br />
* [[Etiprednol]]<br />
** [[Etiprednol dicloacetate|Etiprednol dicloacetate (etiprednol dichloroacetate)]]<!--Etiprednol 17α-(dichloroacetate)--><br />
* [[Fludrocortisone|Fludrocortisone (fludrocortone)]]<br />
** [[Fludrocortisone acetate]]<!--Fludrocortisone 21-acetate--><br />
* [[Fluorometholone]]<br />
** [[Fluorometholone acetate]]<!--Fluorometholone 17α-acetate--><br />
* [[Fluperolone]]<br />
** [[Fluperolone acetate]]<!--Fluperolone 17α-acetate--><br />
* [[Fluprednisolone]]<br />
** [[List of corticosteroid esters#Fluprednisolone esters|Fluprednisolone esters]]<br />
* [[Halopredone]]<br />
** [[Halopredone acetate|Halopredone acetate (halopredone diacetate)]]<!--Halopredone 17α,21-diacetate--><br />
* [[Isoflupredone|Isoflupredone (9α-fluoroprednisolone)]]<br />
** [[Isoflupredone acetate]]<!--Isoflupredone 21-acetate--><br />
* [[Loteprednol]]<br />
* [[Mazipredone|Mazipredone (depersolone)]]<br />
* [[Medrysone]]<br />
* [[Methylprednisolone]]<br />
** [[List of corticosteroid esters#Methylprednisolone esters|Methylprednisolone esters]]<br />
* [[Prebediolone]]<br />
** [[Prebediolone acetate]]<!--Prebediolone 21-acetate--><br />
* [[Prednisolone]]<br />
** [[Prednazate]]<!--Prednisolone 21-(3-carboxypropionate) compound with perphenazine--><br />
** [[Prednazoline]]<!--Prednisolone 21-(dihydrogen phosphate) compound with fenoxazoline--><br />
** [[Prednicarbate|Prednicarbate (prednisolone ethylcarbonate propionate)]]<!--Prednisolone 17α-(ethylcarbonate) 21-propionate--><br />
** [[Prednimustine]]<!--Prednisolone 21-ester of chlorambucil---><br />
** [[Prednisolamate|Prednisolamate (prednisolone diethylaminoacetate)]]<!--Prednisolone 21-(diethylaminoacetate)--><br />
** [[List of corticosteroid esters#Prednisolone esters|Prednisolone esters]]<br />
* [[Prednisone]]<br />
** [[List of corticosteroid esters#Prednisone esters|Prednisone esters]]<br />
* [[Pregnenolone]]<br />
** [[Pregnenolone acetate]]<!--Pregnenolone 3β-acetate--><br />
** [[Pregnenolone succinate|Pregnenolone succinate (pregnenolone hemisuccinate)]]<!--Pregnenolone 3β-(hydrogen succinate)--><br />
* [[Resocortol]]<br />
* [[Tipredane]]<br />
* [[Tixocortol]]<br />
** [[Butixocort|Butixocort (tixocortol butyrate)]]<br />
*** [[Butixocort propionate]]<!--Butixocort 21-propionate--><br />
** [[Tixocortol pivalate]]<!--Tixocortol 21-pivalate--><br />
<br />
* ''Methasones and related (16-substituted):'' [[16α-Methyl-11-oxoprednisolone]]<!--17α,21-Dihydroxy-16α-methylpregna-1,4-diene-3,11,20-trione--><br />
* [[Alclometasone]]<br />
** [[Alclometasone dipropionate]]<!--Alclometasone 17α,21-dipropionate--><br />
* [[Amelometasone]]<br />
* [[Beclometasone|Beclometasone (beclomethasone)]]<br />
** [[List of corticosteroid esters#Beclometasone esters|Beclometasone esters]]<br />
* [[Betamethasone|Betamethasone (betametasone)]]<br />
** [[List of corticosteroid esters#Betamethasone esters|Betamethasone esters]]<br />
** [[Cortobenzolone|Cortobenzolone (betamethasone salicylate)]]<br />
* [[Ciclometasone|Ciclometasone (ciclomethasone, cyclomethasone)]]<br />
* [[Clobetasol]]<br />
** [[Clobetasol propionate]]<!--Clobetasol 17α-propionate--><br />
* [[Clobetasone]]<br />
** [[Clobetasone butyrate]]<!--Clobetasone 17α-butyrate--><br />
* [[Clocortolone]]<br />
** [[List of corticosteroid esters#Clocortolone esters|Clocortolone esters]]<br />
* [[Cloticasone]]<br />
** [[Cloticasone propionate]]<!--Cloticasone 17α-propionate--><br />
* [[Cormetasone|Cormetasone (cormethasone)]]<br />
** [[Cormetasone acetate]]<!--Cormetasone 21-acetate--><br />
* [[Descinolone]]<br />
* [[Desoximetasone|Desoximetasone (desoxymethasone)]]<br />
* [[Dexamethasone|Dexamethasone (dexametasone)]]<br />
** [[List of corticosteroid esters#Dexamethasone esters|Dexamethasone esters]]<br />
* [[Diflorasone]]<br />
** [[Diflorasone diacetate]]<!--Diflorasone 17α,21-diacetate--><br />
* [[Diflucortolone]]<br />
** [[Diflucortolone pivalate]]<!--Diflucortolone 21-pivalate--><br />
** [[Diflucortolone valerate]]<!--Diflucortolone 21-valerate--><br />
* [[Dimesone]]<br />
** [[Dimesone acetate]]<!--Dimesone 21-acetate--><br />
* [[Doxibetasol|Doxibetasol (doxybetasol)]]<br />
* [[Fluclorolone]]<br />
* [[Flumetasone|Flumetasone (flumethasone)]]<br />
** [[Flumetasone acetate]]<!--Flumetasone 21-acetate--><br />
** [[Flumetasone pivalate]]<!--Flumetasone 21-pivalate--><br />
* [[Fluocinolone]]<br />
* [[Fluocortin]]<br />
** [[Fluocortin butyl|Fluocortin butyl (fluocortin butylate)]]<!--Fluocortin 21-butylate--><br />
* [[Fluocortolone]]<br />
** [[List of corticosteroid esters#Fluocortolone esters|Fluocortolone esters]]<br />
* [[Fluprednidene|Fluprednidene (fluprednylidene)]]<br />
** [[Fluprednidene acetate]]<!--Fluprednidene 21-acetate--><br />
* Fluticasone<br />
** [[Fluticasone furoate]]<!--Fluticasone 17α-(2-furoate)--><br />
** [[Fluticasone propionate]]<!--Fluticasone 17α-propionate--><br />
* [[Halocortolone]]<br />
* [[Halometasone]]<br />
* [[Icometasone]]<br />
** [[Icometasone enbutate|Icometasone enbutate (icometasone butyrate acetate)]]<!--Icometasone 17α-butyrate 21-acetate--><br />
* [[Isoprednidene]]<br />
* [[Locicortolone|Locicortolone (locicortone)]]<br />
** [[Locicortolone dicibate|Locicortolone dicibate (locicortone dicibate)]]<!--Locicortolone 21-dicibate (locicortolone 21-(dicyclohexylmethylcarbonate))--><br />
* [[Meclorisone]]<br />
** [[Meclorisone dibutyrate]]<!--Meclorisone 17α,21-dibutyrate--><br />
* [[Meprednisone|Meprednisone (methylprednisone)]]<br />
** [[Meprednisone acetate]]<!--Meprednisone 21-acetate--><br />
** [[Meprednisone hydrogen succinate|Meprednisone hydrogen succinate (methylprednisone hemisuccinate)]]<!--Meprednisone 21-(hemisuccinate)--><br />
* [[Mometasone]]<br />
** [[Mometasone furoate]]<!--Mometasone 17α-(2-furoate)--><br />
* [[Paramethasone]]<br />
** [[Paramethasone acetate]]<!--Paramethasone 21-acetate--><br />
** [[Paramethasone disodium phosphate]]<!--Paramethasone 21-(disodium phosphate)--><br />
** [[Paramethasone phosphate]]<!--Paramethasone 21-phosphate--><br />
* [[Prednylidene]]<br />
** [[Prednylidene diethylaminoacetate]]<!--Prednylidene 21-(diethylaminoacetate)--><br />
* [[Rimexolone]]<br />
* [[Ticabesone]]<br />
** [[Ticabesone propionate]]<!--Ticabesone 17α-propionate--><br />
* [[Timobesone]]<br />
** [[Timobesone acetate]]<!--Timobesone 17α-acetate--><br />
* [[Triamcinolone]]<br />
** [[Triamcinolone diacetate]]<!--Triamcinolone 16α,21-diacetate--><br />
* [[Ulobetasol|Ulobetasol (halobetasol)]]<br />
** [[Ulobetasol propionate]]<!--Ulobetasol 17α-propionate--><br />
* [[Vamorolone]]<br />
<br />
* ''Cyclic ketals (16,17-cyclized):'' [[Acrocinonide|Acrocinonide (triamcinolone acroleinide)]]<br />
* [[Amcinafal|Amcinafal (triamcinolone pentanonide)]]<br />
* [[Amcinafide|Amcinafide (triamcinolone acetophenide)]]<br />
* [[Amcinonide|Amcinonide (triamcinolone acetate cyclopentanonide)]]<br />
* [[Budesonide]]<br />
* [[Ciclesonide]]<br />
* [[Cicortonide]]<br />
* [[Deflazacort|Deflazacort (azacort)]]<br />
* [[Descinolone acetonide]]<!--Descinolone 16α,17α-acetonide--><br />
* [[Desonide|Desonide (hydroxyprednisolone acetonide)]]<br />
** [[Desonide disodium phosphate]]<!--Desonide 21-(disodium phosphate)--><br />
** [[Desonide pivalate]]<!--Desonide 21-pivalate--><br />
* [[Dexbudesonide]]<br />
* [[Drocinonide]]<br />
** [[Drocinonide phosphate]]<!--Drocinonide 21-phosphate--><br />
* [[Fluazacort]]<br />
* [[Fluclorolone acetonide|Fluclorolone acetonide (flucloronide)]]<!--Fluclorolone 16α,17α-acetonide--><br />
* [[Fludroxycortide|Fludroxycortide (flurandrenolone, flurandrenolide)]]<br />
* [[Flumoxonide]]<br />
* [[Flunisolide]]<br />
** [[Flunisolide acetate]]<!--Flunisolide 21-acetate--><br />
* [[Fluocinolone acetonide]]<!--Fluocinolone 16α,17α-acetonide--><br />
** [[Ciprocinonide|Ciprocinonide (fluocinolone acetonide cyclopropylcarboxylate)]]<!--Fluocinolone 16α,17α-acetonide 21-cyclopropylcarboxylate--><br />
** [[Fluocinonide|Fluocinonide (fluocinolide, fluocinolone acetonide acetate)]]<!--Fluocinolone acetonide 21-acetate--><br />
** [[Procinonide|Procinonide (fluocinolone acetonide propionate)]]<!--Fluocinolone acetonide 21-propionate--><br />
* [[Formocortal]]<br />
* [[Halcinonide]]<br />
* [[Itrocinonide]]<br />
* [[Rofleponide]]<br />
** [[Rofleponide palmitate]]<!--Rofleponide 11β-palmitate--><br />
* [[Tralonide]]<br />
* [[Triamcinolone acetonide]]<!--Triamcinolone 16α,17α-acetonide--><br />
** [[Flupamesone|Flupamesone (triamcinolone acetonide metembonate)]]<br />
** [[List of corticosteroid esters#Triamcinolone acetonide esters|Triamcinolone acetonide esters]]<br />
* [[Triamcinolone aminobenzal benzamidoisobutyrate|Triamcinolone aminobenzal benzamidoisobutyrate (TBI-PAB)]]<!--51241-99-7; Triamcinolone 16α,17α-(((4-(dimethylamino)phenyl)methylene)dioxy) 21-(benzoyl-β-aminoisobutyrate)--><br />
* [[Triclonide]]<br />
<br />
* ''Others/atypical (other expanded steroid ring systems, homosteroids, and non-pregnane steroids):'' [[Cortisuzol]]<br />
* [[Cortivazol]]<br />
* [[Domoprednate]]<br />
* [[Naflocort]]<br />
* [[Nicocortonide]]<br />
** [[Nicocortonide acetate]]<!--Nicocortonide 21-acetate--><br />
* [[Nivacortol|Nivacortol (nivazol)]]<br />
* [[Oxisopred]]<br />
* [[RU-26988]]<br />
* [[RU-28362]]<br />
<br />
* ''Non-corticosteroids with some glucocorticoid activity:'' [[15β-Hydroxycyproterone acetate]]<br />
* [[17α-Hydroxyprogesterone]]<br />
* [[Bromoketoprogesterone]]<br />
* [[Chlormadinone acetate]]<br />
* [[Cyproterone]]<br />
* [[Cyproterone acetate]]<br />
* [[Danazol]]<br />
* [[Delmadinone acetate]]<br />
* [[Desogestrel]]<br />
* [[DU-41165]]<br />
* [[Etonogestrel]]<br />
* [[Flugestone]]<br />
* [[Flugestone acetate|Flugestone acetate (flurogestone acetate)]]<br />
* [[Fluoromedroxyprogesterone acetate]]<br />
* [[Fluoxymesterone]]<br />
* [[Gestodene]]<br />
* [[Medrogestone]]<br />
* [[Medroxyprogesterone acetate]]<br />
* [[Megestrol acetate]]<br />
* [[Metribolone]]<br />
* [[Norgestomet]]<br />
* [[Osaterone acetate]]<br />
* [[Progesterone]]<br />
* [[Promegestone]]<br />
* [[RU-2309]]<br />
* [[Quingestrone]]<br />
* [[Segesterone acetate|Segesterone acetate (nestorone)]]<br />
* [[Tetrahydrogestrinone]]<br />
<br />
* ''Nonsteroidal glucocorticoids:'' [[AZD-5423]]<br />
* [[GSK-9027]]<br />
<br />
| group2 = Mixed<br />({{abbrlink|SEGRMs|Selective glucocorticoid receptor agonists}})<br />
| list2 =<br />
* [[Dagrocorat]]<br />
* [[Fosdagrocorat]]<br />
* [[Mapracorat]]<br />
<br />
| group3 = [[Antiglucocorticoid|Antagonist]]s<br />
| list3 =<br />
* [[7α-Hydroxy-DHEA]]<br />
* [[17α-Methylprogesterone]]<br />
* [[Aglepristone]]<br />
* [[Asoprisnil]]<br />
* [[Asoprisnil ecamate]]<br />
* [[C108297]]<br />
* [[C113176]]<br />
* [[CORT-108297]]<br />
* [[Cyproterone acetate]]<br />
* [[Dazucorilant]]<br />
* [[Exicorilant|Exicorilant (CORT-125281)]]<br />
* [[Guggulsterone]]<br />
* [[Ketoconazole]]<br />
* [[Lilopristone]]<br />
* [[LLY-2707]]<!--Non-steroidal--><br />
* [[Metapristone|Metapristone (RU-42633)]]<br />
* [[Miconazole]]<br />
* [[Mifepristone|Mifepristone (RU-486)]]<br />
* [[Miricorilant|Miricorilant (CORT-118335)]]<br />
* [[Onapristone]]<br />
* [[ORG-34116]]<br />
* [[ORG-34517|ORG-34517 (SCH-900636)]]<br />
* [[Org 34850|ORG-34850]]<br />
* [[Pregnenolone 16α-carbonitrile]]<br />
* [[Relacorilant|Relacorilant (CORT-125134)]]<br />
* [[RTI 3021–012]]<br />
* [[RTI 3021–022]]<br />
* [[Telapristone]]<br />
* [[Tibolone]]<br />
* [[Toripristone]]<br />
* [[Ulipristal acetate]]<br />
* [[Zavacorilant]]<br />
<br />
| group4 = Others<br />
| list4 =<br />
* ''Antisense oligonucleotides:'' [[IONIS-GCCRRx|IONIS-GCCR<sub>Rx</sub> (ISIS-426115)]]<br />
<br />
}}<br />
<br />
| below = <br />
;See also<br />
: [[Template:Receptor modulators|Receptor/signaling modulators]] <br />
: [[Template:Glucocorticoids and antiglucocorticoids|Glucocorticoids and antiglucocorticoids]]<br />
: [[Template:Mineralocorticoid receptor modulators|Mineralocorticoid receptor modulators]] <br />
: [[List of corticosteroids]]<br />
<br />
}}<noinclude><br />
{{collapsible option}}<br />
[[Category:Drug templates by receptor, channel, or pump]]<br />
[[Category:Glucocorticoids]]<br />
</noinclude></div>
alpha>Indicwiki