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Template:GHB receptor modulators - Revision history
2026-06-29T08:09:10Z
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2023-08-08T01:33:00Z
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Indicwiki
https://www.vigyanwiki.in/index.php?title=Template:GHB_receptor_modulators&diff=238092&oldid=prev
alpha>Indicwiki: Created page with "{{Navbox | name = GHB receptor modulators | title = γ-Hydroxybutyric acid}} receptor modulators | state = {{{state<include..."
2023-07-19T05:46:41Z
<p>Created page with "{{Navbox | name = GHB receptor modulators | title = <a href="/index.php?title=GHB_receptor&action=edit&redlink=1" class="new" title="GHB receptor (page does not exist)">{{abbr|GHB|γ-Hydroxybutyric acid}} receptor</a> <a href="/index.php?title=Receptor_modulator&action=edit&redlink=1" class="new" title="Receptor modulator (page does not exist)">modulators</a> | state = {{{state<include..."</p>
<p><b>New page</b></p><div>{{Navbox<br />
| name = GHB receptor modulators<br />
| title = [[GHB receptor|{{abbr|GHB|γ-Hydroxybutyric acid}} receptor]] [[receptor modulator|modulator]]s<br />
| state = {{{state<includeonly>|collapsed</includeonly>}}}<br />
| bodyclass = hlist<br />
| groupstyle = text-align:center;<br />
<br />
| group1 = [[Receptor (biochemistry)|Receptor]]<br /><small>([[Ligand (biochemistry)|ligand]]s)</small><br />
| list1 = {{Navbox|subgroup<br />
| groupstyle = text-align:center;<br />
| groupwidth = 4em;<br />
<br />
| group1 = {{abbrlink|GHBR|GHB receptor}}<br />
| list1 = <br />
* '''Agonists:''' ''Main site:'' [[1,4-Butanediol|1,4-BD]]<!--Prodrug to GHB--><br />
* [[3-Hydroxyphenylacetic acid|3-HPA]]<br />
* [[Aceburic acid|Aceburic acid (GHB acetate)]]<!--Prodrug to GHB--><br />
* [[1,4-Butanediol diacetate|BDDA (DABD)]]<!--Prodrug to GHB--><br />
* [[Ethyl-4-acetoxybutanoate|EAB]]<!--Prodrug to GHB--><br />
* [[γ-Butyrolactone|GBL]]<!--Prodrug to GHB--><br />
* [[γ-Crotonolactone|GCL]]<!--Prodrug to GHC--><br />
* [[γ-Hydroxybutyric acid|GHB]]<br />
* [[γ-Hydroxybutaldehyde|GHBAL]]<!--Prodrug to GHB--><br />
* [[γ-Hydroxyvaleric acid|GHV (4-methyl-GHB)]]<br />
* [[γ-Valerolactone|GVL]]<!--Prodrug to GHV--><br />
* [[HOCHCA]]<br />
* [[HOCPCA]]<br />
* [[Methyl-4-acetoxybutanoate|MAB]]<!--Prodrug to GHB--><br />
* [[NCS-356]]<!--γ-(p-chlorobenzyl)-γ-hydroxybutanoic acid--><br />
* [[NCS-435]]<!--γ-(p-methoxybenzyl)-γ-hydroxybutyric acid--><br />
* [[Sodium oxybate]]<br />
* [[T-HCA|T-HCA (GHC)]]<!--γ-hydroxycrotonic acid (GHC)--><br />
* [[Tetrahydrofuran|THF]]<!--Prodrug--><!--PMID: 17331547--><br />
* [[UMB58]]<!--5-hydroxypentanoic acid--><br />
* [[UMB66]]<!--3-chloropropanoic acid--><br />
* [[UMB68]]<!--4-hydroxy-4-methylpentanonic acid--><br />
* [[UMB72]]<!--4-(3-phenylpropyloxy)butyric acid--><br />
* [[UMB73]]<!--4-benzyloxybutyric acid--><br />
* [[UMB86]]<!--4-hydroxy-4-napthylbutanoic acid-->; ''Positive allosteric modulators:'' [[Catechin|(+)-Catechin]]<br />
* [[Monastrol]]<br />
<br />
* '''Antagonists:''' ''Main site:'' [[Gabazine|Gabazine (SR-95531)]]<!--PMID: 22753476--><br />
* [[NCS-382]]<br />
<br />
* '''Unknown/unsorted:''' ''Main site:'' [[2-Hydroxyphenylacetic acid|2-HPA]]<br />
* [[3-Methyl-GHB]]<br />
* [[3-Methyl-THCA]]<br />
* [[4-Benzyl-GHB]]<br />
* [[4-Hydroxy-4-phenylbutyric acid|4-HPBA]]<br />
* [[4-Methyl-THCA]]<br />
* [[4-Phenyl-GHB]]<br />
* [[4-Phenyl-THCA]]<br />
* [[Amisulpride]]<br />
* [[azido-BnOPh-GHB]]<br />
* [[BnOPh-GHB]]<!--4-hydroxy-4-[4-(2-iodobenzyloxy)phenyl]butanoate--><br />
* [[δ-Hydroxyvaleric acid|DHV]]<br />
* [[δ-Valerolactone|DVL]]<!--Prodrug--><br />
* [[γ-Thiobutyrolactone|GTBL]]<!--Prodrug--><br />
* [[Levosulpiride]]<br />
* [[NCS-400]]<!--5-hydroxy-5,7,8,9-tetrahydro-6H-benzo[a][7]annulen-6-yl ethanoic acid--><br />
* [[Prochlorperazine]]<br />
* [[Sulpiride]]<br />
* [[Sultopride]]<br />
* [[UMB108]]<br />
* [[UMB109]]<br />
* [[UMB119]]<br />
<br />
| group2 = {{abbrlink|GABA<sub>B</sub>|γ-Aminobutyric acid B receptor}}<br />
| list2 =<br />
* See [[Template:GABA receptor modulators|here]] instead.<br />
<br />
}}<br />
<br />
| group2 = [[Neurotransmitter transporter|Transporter]]<br /><small>([[Reuptake inhibitor|blocker]]s)</small><br />
| list2 = {{Navbox|subgroup<br />
| groupstyle = text-align:center;<br />
| groupwidth = 4em;<br />
<br />
| group1 = {{abbrlink|MCTs|Monocarboxylate transporters}}<!--Across BBB--><br />
| list1 =<br />
* [[α-Ketoisocaproate]]<br />
* [[Acetoacetic acid]]<br />
* [[AR-C155858]]<br />
* [[Atorvastatin]]<br />
* [[Benzoic acid]]<br />
* [[β-Hydroxybutyric acid|BHB]]<br />
* [[Butyric acid]]<br />
* [[α-Cyano-4-hydroxycinnamic acid|CHCA]]<br />
* [[4,40-dibenzamidostilbene-2,20-disulphonate|DBDS]]<br />
* [[DIDS]]<br />
* [[Hexanoic acid]]<br />
* [[Lactic acid]]<br />
* [[Luteolin]]<br />
* [[Niflumic acid]]<br />
* [[5-Nitro-2-(3-phenylpropylamino)benzoic acid|NPPB]]<br />
* [[Phenylpyruvic acid]]<br />
* [[Phloretin]]<br />
* [[Probenecid]]<br />
* [[Pyruvic acid]]<br />
* [[Quercetin]]<br />
* [[Salicylic acid]]<br />
* [[Simvastatin]]<br />
* [[Sodium valproate]]<br />
* [[Valproic acid]]<br />
<br />
| group2 = {{abbrlink|SMCTs|Sodium-coupled monocarboxylate transporters}}<!--Across BBB--><br />
| list2 =<br />
* [[Benzoic acid]]<br />
* [[β-Hydroxybutyric acid|BHB]]<br />
* [[Butyric acid]]<br />
* [[Fenoprofen]]<br />
* [[Ibuprofen]]<br />
* [[Ketoprofen]]<br />
* [[Mesalazine|Mesalazine (5-ASA)]]<br />
* [[Naproxen]]<br />
* [[Niacin (substance)|Nicotinic acid]]<br />
* [[Probenecid]]<br />
* [[Propionic acid]]<br />
* [[Pyruvic acid]]<br />
* [[Salicyclic acid]]<br />
<br />
| group3 = {{abbrlink|VIATT|Vesicular inhibitory amino acid transporter}}<br />
| list3 =<br />
* [[β-Alanine]]<br />
* [[Bafilomycin A1]]<br />
* [[Butyric acid]]<br />
* [[Evans blue (dye)|Evans blue]]<br />
* [[GABA]]<!--Competitive--><br />
* [[Glycine]]<!--Competitive--><br />
* [[Nigericin]]<br />
* [[Nipecotic acid]]<br />
* [[Valinomycin]]<br />
* [[Vigabatrin]]<br />
<br />
}}<br />
<br />
| group3 = [[Enzyme]]<br /><small>([[Enzyme inhibitor|inhibitor]]s)</small><br />
| list3 = {{Navbox|subgroup<br />
| groupstyle = text-align:center;<br />
| groupwidth = 4em;<br />
<br />
| group1 = {{abbrlink|SSR|Succinic semialdehyde reductase}}<br />
| list1 = <br />
* [[Quercetin]]<br />
<br />
| group2 = {{abbrlink|GHBDH|4-Hydroxybutyrate dehydrogenase}}<br />
| list2 = <br />
* [[α-Ketoisocaproic acid]]<br />
* [[Ethosuximide]]<br />
* [[Phenylacetate]]<br />
* [[Salicylic acid]]<br />
* [[Valproic acid]]<br />
<br />
* ''Enhancers:'' [[Glucuronic acid|<small>D</small>-Glucuronic acid]]<br />
<br />
| group3 = {{abbrlink|HOT|Hydroxyacid-oxoacid transhydrogenase}}<!--GHB transhydrogenase; mitochondrial enzyme--><br />
| list3 = <br />
* [[Cyanide]]<br />
* [[Phenanthroline]]<br />
<br />
| group4 = {{abbrlink|ADH|Alcohol dehydrogenase}}<br />
| list4 = <br />
* [[Cimetidine]]<br />
* [[Ethanol]]<br />
* [[Fomepizole|Fomepizole (4-methylpyrazole)]]<br />
* [[Pyrazole]]<br />
<br />
| group5 = {{abbrlink|ALDH|Aldehyde dehydrogenase}}<br />
| list5 = <br />
* [[Acetaldehyde]]<br />
* [[Cimetidine]]<br />
* [[Cyanamide]]<br />
* [[Disulfiram]]<br />
* [[Prunetin]]<br />
<br />
}}<br />
<br />
| below = <br />
;See also<br />
: ''[[Template:Receptor modulators|Receptor/signaling modulators]]''<br />
: ''[[Template:GABA receptor modulators|GABA receptor modulators]]''<br />
: ''[[Template:Glutamate receptor modulators|Glutamate receptor modulators]]''<br />
: ''[[Template:Glycine receptor modulators|Glycine receptor modulators]]''<br />
<br />
}}<noinclude><br />
{{collapsible option}}<br />
[[Category:Drug templates by receptor, channel, or pump]]<br />
[[Category:Gamma-Hydroxybutyric acid]]<br />
</noinclude></div>
alpha>Indicwiki